Sca2 converter

Connecting wide devices to a narrow bus or narrow devices to a wide bus must be done with the proper adapter which takes the termination problems into account. Wide scsi devices will work just fine using only the first byte, and therefore can be used on a narrow bus cable as long as their connected using a scsi adapter with high byte termination. Narrow devices can be used on a wide bus, without problems depending on whether or not they are connected to an "LVD" Low Voltage Differential segment.

None are made anymore that we know of. If you really must have one you may end up paying quite a bit more on ebay than the original list price. This is because as the gene is passed down from parent to child, the number of CAG repeats often increases. In general, the more repeats a person has, the earlier symptoms begin.

This phenomenon is called anticipation. People with 32 or 33 repeats tend to develop symptoms in late adulthood, while people with more than 45 repeats often have symptoms by their teens.

For some reason, the number of repeats tend to increase more when the gene is inherited from a person's father than when inherited from a person's mother. Diagnosis Diagnosis. The intended audience for the GTR is health care providers and researchers. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional. Orphanet lists international laboratories offering diagnostic testing for this condition.

Click on the title above to view this resource. Treatment Treatment. Treatment of spinocerebellar ataxia 2 SCA2 is supportive and aims to help the affected person maintain their independence and avoid injury.

It is recommended that people with SCA2 remain physically active, maintain a healthy weight, use adaptive equipment as needed, and avoid alcohol and medications that affect cerebellar function. Adaptive equipment may include canes or other devices to help with walking and mobility. People with SCA2 may develop difficulty speaking and may need to use computerized devices or writing pads to help with communication.

Levodopa may be prescribed to help with some of the movement problems e. Find a Specialist Find a Specialist. Healthcare Resources To find a medical professional who specializes in genetics, you can ask your doctor for a referral or you can search for one yourself.

You can also learn more about genetic consultations from MedlinePlus Genetics. The National Ataxia Foundation , a nonprofit organization dedicated to improving the lives of persons affected by ataxia, provides lists of neurologists, ataxia clinics, and movement disorder clinics.

Research Research. Clinical Research Resources ClinicalTrials. Click on the link to go to ClinicalTrials. Please note: Studies listed on the ClinicalTrials. We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study. Orphanet lists European clinical trials, research studies, and patient registries enrolling people with this condition.

The goal of the CoRDS registry is to connect as many patients and researchers as possible to help advance treatments and cures for rare diseases. The CoRDS registry is free for patients to enroll and for researchers to access. Organizations Organizations. Organizations Supporting this Disease. Do you know of an organization? Living With Living With. This initiative speeds up the processing of disability claims for applicants with certain medical conditions that cause severe disability.

More information about Compassionate Allowances and applying for Social Security disability is available online. Learn More Learn More. This website is maintained by the National Library of Medicine. The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers. Click on the link to view information on this topic.

In-Depth Information GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.

The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health.

Visit the website to explore the biology of this condition. The Neuromuscular Disease Center at Washington University provides information about spinocerebellar ataxia 2. Each entry has a summary of related medical articles.

It is meant for health care professionals and researchers. Orphanet is a European reference portal for information on rare diseases and orphan drugs.

Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss Spinocerebellar ataxia 2. Click on the link to view a sample search on this topic. Submit a new question My father has been diagnosed with this condition. See answer What type of diet is recommended for people with spinocerebellar ataxia type 2? See answer Is there a cure for spinocerebellar ataxia type 2?

See answer Have a question? References References. Pulst SM. Spinocerebellar ataxia type 2. Genetics Home Reference. Spinocerebellar ataxia 2 SCA2. For the quite ubiquitously expressed ataxin-2, a subcellular localization at the Golgi, the endoplasmic reticulum and the plasma membrane, in interaction with proteins of mRNA translation and of endocytosis have been observed.

As a first victim of SCA2 degeneration, cerebellar Purkinje neurons may be preferentially susceptible to alterations of these subcellular pathways, and therefore our review aims to portray the particular profile of the SCA2 disease process and correlate it to the specific features of ataxin Abstract Spinocerebellar ataxia type 2 SCA2 is an autosomal dominantly inherited, neurodegenerative disease.